Body Pharm Melanotan II 20mg

Overview

Body Pharm Melanotan II 20 mg is a sealed, pre-filled multi-dose research pen containing 20 mg of Melanotan II in solution. Melanotan II is a synthetic cyclic heptapeptide analogue of α-melanocyte-stimulating hormone (α-MSH), Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2, developed at the University of Arizona as a conformationally constrained, protease-resistant melanocortin ligand.

The pen is a laboratory research material. It is supplied strictly for laboratory research and is not for human or veterinary use. It is not a medicine, food, dietary supplement or cosmetic, and no medical, therapeutic or performance claims are made or implied. No dosing information is provided.

Research background

Melanotan II is a non-selective agonist at the melanocortin receptors MC1R, MC3R, MC4R and MC5R [1]. In the laboratory it is used as a reference ligand in melanocortin-receptor binding and cAMP-signalling assays, in melanocyte-culture studies of MC1R-mediated melanogenesis, and in preclinical models of central melanocortin signalling [1][2]. Its lactam-bridged cyclic structure gives it substantially greater potency and stability than linear α-MSH in these assays, which is why it is a common comparator in structure–activity work on the melanocortin system.

Specification

• Compound: Melanotan II
• Declared quantity: 20 mg per pen
• CAS: 121062-08-6
• Molecular formula: C50H69N15O9
• Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2
• Format: Solution, pre-filled multi-dose research pen

Quality documentation

Every batch is HPLC-tested for purity and identity. The batch-specific Certificate of Analysis is published on this page and on our Certificates of Analysis page, and the batch number is printed on the pen label.

Storage and handling

Store refrigerated at 2–8 °C. Protect from light. Do not freeze. Handle only with appropriate personal protective equipment in a laboratory setting and dispose of the pen as laboratory sharps waste. Keep out of reach of children and animals.

Supply, dispatch and returns

Dispatched from the UK by tracked Royal Mail in plain outer packaging; most UK orders arrive within 1–3 working days. Shipping is free on UK pen orders. Unused, unopened pens with the seal intact may be returned within 14 days of delivery; opened pens cannot be returned. See shipping and returns.

Frequently Asked Questions

Is Melanotan II for human use?

No. Body Pharm Melanotan II is supplied strictly for laboratory research and is not for human, veterinary or cosmetic use. No dosing or administration information is provided.

What receptors does Melanotan II act on?

Melanotan II is a non-selective agonist at the melanocortin receptors MC1R, MC3R, MC4R and MC5R.

How is purity verified?

Each batch is HPLC-tested for purity and identity; the Certificate of Analysis for that batch is published on this page.

How should the pen be stored?

Refrigerated at 2–8 °C, protected from light, never frozen.

References

1. Hadley ME, Dorr RT. Melanocortin peptide therapeutics: historical milestones, clinical studies and commercialization. Peptides. 2006. pubmed.ncbi.nlm.nih.gov/16269200
2. PubChem compound summary: Melanotan II. pubchem.ncbi.nlm.nih.gov/compound/Melanotan-II