Body Pharm Somatropin 100 (HGH)

Overview

Body Pharm Somatropin 100 (HGH) is a sealed, pre-filled multi-dose research pen containing 100 IU of somatropin — recombinant human growth hormone, the 191-amino-acid, 22 kDa single-chain polypeptide identical in sequence to pituitary-derived human growth hormone — in solution.

The pen is a laboratory research material. It is supplied strictly for laboratory research and is not for human or veterinary use. It is not a medicine, food, dietary supplement or cosmetic, and no medical, therapeutic or performance claims are made or implied. No dosing information is provided.

Research background

Growth hormone binds the growth-hormone receptor (GHR), a class 1 cytokine receptor, inducing receptor dimerisation and JAK2/STAT5 signalling; hepatic IGF-1 production is the canonical downstream readout [1]. In the laboratory recombinant somatropin is used as the reference ligand in GHR binding and signalling assays, in IGF-1 axis studies and in preclinical models of somatotropic-axis biology [1][2].

Somatropin acts at the growth-hormone receptor itself, downstream of the GHRH-receptor and ghrelin-receptor ligands (Tesamorelin, CJC-1295 + Ipamorelin) that regulate its secretion in the model system. Declared quantity is expressed in international units (IU) per the WHO international standard for somatropin; 1 mg of somatropin corresponds to 3 IU.

Specification

• Compound: Somatropin (recombinant human growth hormone, 191 aa)
• Declared quantity: 100 IU per pen
• CAS: 12629-01-5
• Molecular formula: C990H1528N262O300S7 (MW ≈ 22,124 Da)
• Format: Solution, pre-filled multi-dose research pen
• Also available: Somatropin 40 IU (waitlist)

Quality documentation

Every batch is HPLC-tested for purity and identity. The batch-specific Certificate of Analysis is published on this page and on our Certificates of Analysis page, and the batch number is printed on the pen label.

Storage and handling

Store refrigerated at 2–8 °C. Protect from light. Do not freeze; do not shake (protein aggregation). Handle only with appropriate personal protective equipment in a laboratory setting and dispose of the pen as laboratory sharps waste. Keep out of reach of children and animals.

Supply, dispatch and returns

Dispatched from the UK by tracked Royal Mail in plain outer packaging; most UK orders arrive within 1–3 working days. Shipping is free on UK pen orders. Unused, unopened pens with the seal intact may be returned within 14 days of delivery; opened pens cannot be returned. See shipping and returns.

Frequently Asked Questions

Is Somatropin 100 for human use?

No. It is supplied strictly for laboratory research and is not for human or veterinary use. No dosing or administration information is provided.

Why is the quantity in IU rather than mg?

Somatropin activity is standardised against the WHO international standard and conventionally declared in international units; 1 mg corresponds to 3 IU.

How is purity verified?

Each batch is HPLC-tested for purity and identity; the Certificate of Analysis for that batch is published on this page.

How should the pen be stored?

Refrigerated at 2–8 °C, protected from light, never frozen and never shaken.

References

1. Brooks AJ, Waters MJ. The growth hormone receptor: mechanism of activation and clinical implications. Nat Rev Endocrinol. 2010. pubmed.ncbi.nlm.nih.gov/20664532
2. Ranke MB, Wit JM. Growth hormone — past, present and future. Nat Rev Endocrinol. 2018. pubmed.ncbi.nlm.nih.gov/29449663